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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Anal Cell Pathol (Amst). 2012;35(4):205–227. doi: 10.3233/ACP-2011-0050

Figure 14.

Figure 14

MRM imaging at 19.5 μm resolution allows discerning cardiac defects in a mouse with conditional ablation of Smo receptor gene. From most cranial to most caudal slices, the arrows point to (A, B) outflow tract abnormalities in the mutant mouse, which fails to branch into the aorta and pulmonary trunk (C, D) an open septum defect (E, F), absence of DMP in mutant mouse. (A′, B′) present surface rendering of the segmented heart (ventral view) and abnormal outflow tract in the mutant in comparison to the wild type control. (E′, F′) illustrate the absence of DMP (in a dorsal view of the heart). Reproduced with permission from (Petiet, Kaufman et al. 2008). Copyright 2008 National Academy of Sciences, USA.