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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Anal Cell Pathol (Amst). 2012;35(4):205–227. doi: 10.3233/ACP-2011-0050

Figure 16.

Figure 16

MRM can be used to identify differences in cardiac function among strains of mice. Here the C57BL/6 was found to be slightly hypertrophic compared to the DBA/2 and DBA/2 CSQ+. The ventricular volumes were used to determine significant differences in left ventricle ejection fraction, smallest for DBA2 CSQ+, and largest for DBA/2, while the right ventricle ejection fraction was significantly higher in DBA/2. Significant differences are also apparent in the right ventricle end systole, larger in DBA2 CSQ+. These differences are also apparent from surface renderings of the segmented heart compartments. Reproduced with permission from (Bucholz, Ghaghada et al. 2010).