Table 2.

Effects of Ca²⁺ current blockers on action potentials

Apex	latency (ms)	amplitude (mV)	width (ms)	Base	latency (ms)	amplitude (mV)	width (ms)
Control (n = 7)	3.2 ± 1.4	93 ± 6	1.8 ± 0.4	(n = 6)	8.4 ± 1.4	111 ± 10	9.2 + 1.4
4-AP	3.0 ± 0.7	54 ± 11	3.8 ± 0.5		6.5 ± 0.7	78 ± 12*	11.6 + 1.5
4-AP + mibefradil	3.5 ± 1.1	39 ± 9**	5.2 ± 0.9*		13.5 ± 2.6*	46 ± 15**	18.5 + 1.8**
Control (n = 8)	4.1 ± 1.2	94 ± 8	1.9 ± 0.4	(n = 8)	9.3 ± 0.9	107 ± 12	8.8 + 1.6
4-AP	3.9 ± 1.5	71 ± 5	3.6 ± 0.3		6.7 ± 1.1	81 ± 9	10.2 + 0.5
4-AP + rSNX	7.0 ± 2.0*	67 ± 10*	6.2 ± 0.3**		3.4 ± 0.4*	68 ± 16**	16 + 1.4*
Control (n = 6)	4.4 ± 1.6	105 ± 13	1.8 ± 0.6	(n = 5)	9.5 ± 1.8	110 ± 12	8.6 + 1.4
4-AP	3.9 ± 1.1	78 ± 12	2.9 ± 0.5		9.9 ± 2.3	86 ± 16	10.4 + 1.6
4-AP + ω-Agatoxin	9.1 ± 2.3*	43 ± 10**	10 ± 1.5**		5.1 ± 0.5*	57 ± 14**	18.9 + 2.2**
Control (n = 7)	3.7 ± 1.3	97 ± 7	2.0 ± 0.3	(n = 7)	8.2 ± 1.3	105 ± 15	7.9 + 1.5
4-AP	3.2 ± 1.1	82 ± 16	3.2 ± 1.4		7.1 ± 1.5	89 ± 16	9.1 + 2.1
4-AP + ω-Conotoxin	7.4 ± 1.3*	78 ± 20	4.1 ± 1.5		11.8 ± 0.5*	85 ± 20	12 + 4.4
Control (n = 8)	4.0 ± 1.6	101 ± 14	1.7 ± 0.5	(n = 9)	7.9 ± 1.8	121 ± 26	10 + 1.3
4-AP	3.9 ± 1.4	89 ± 12	3.4 ± 0.6		7.2 ± 2.1	80 ± 13	13 + 0.8
4-AP + Nimodipine	6.8 ± 0.5*	71 ± 5*	8.1 ± 0.7*		3.1 ± 1.1*	51 ± 7*	19 + 1.7*

4-AP 4-aminopyridine,

^*p < 0.05;

^**p < 0.01 ; n = number of cells.