Table 1.
PO2 | PCO2 | pH | ||
---|---|---|---|---|
Time
Control |
baseline | 250 ± 7 | 47.4 ± 1.5 | 7.36 ± 0.01 |
60 min | 253 ± 3 | 47.4 ± 1.5 | 7.35 ± 0.01 | |
Neural apnea
+ pre-aCSF |
baseline | 253 ± 10 | 47.3 ± 1.2 | 7.35 ± 0.01 |
60 min | 249 ± 13 | 47.6 ± 1.3 | 7.34 ± 0.01 | |
Neural apnea
+ pre-PKCζ-PS |
baseline | 239 ± 5 | 47 ± 1.9 | 7.34 ± 0.01 |
60 min | 246 ± 6 | 46.4 ± 1.9 | 7.33 ± 0.02 | |
Neural apnea
+ pre-scrPKCζ-PS |
baseline | 240 ± 12 | 49.4 ± 1.5 | 7.34 ± 0.02 |
60 min | 241 ± 10 | 49.6 ± 1.6 | 7.33 ± 0.01 | |
IH
+ pre-PKCζ-PS |
baseline | 266 ± 12 | 50.3 ± 1.2 | 7.34 ± 0.01 |
60 min | 270 ± 11 | 50.6 ± 1 | 7.30 ± 0.01 | |
IH
+ pre-scrPKCζ-PS |
baseline | 277 ± 21 | 48.6 ± 2 | 7.37 ± 0.04 |
60 min | 270 ± 11 | 48.9 ± 2 | 7.33 ± 0.01 | |
Neural apnea
+ PKCζ-PS-10 |
baseline | 276 ± 24 | 51.8 ± 0.9 | 7.34 ± 0.01 |
90 min | 297 ± 7 | 51.4 ± 1 | 7.34 ± 0.01 | |
Neural apnea
+ scrPKCζ-PS-10 |
baseline | 276 ± 17 | 49.2 ± 1 | 7.33 ± 0.01 |
90 min | 281 ± 19 | 49.8 ± 1 | 7.34 ± 0.02 | |
IH
+ PKCζ-PS-10 |
baseline | 254 ± 28 | 47.3 ± 2.6 | 7.35 ± 0.02 |
90 min | 288 ± 13 | 47.1 ± 2.1 | 7.36 ± 0.01 | |
IH
+ scrPKCζ-PS-10 |
baseline | 265 ± 50 | 46.7 ± 1.9 | 7.36 ± 0.01 |
90 min | 286 ± 25 | 46.6 ± 1.7 | 7.38 ± 0.01 | |
Neural apnea
+ PKCζ-PS-45 |
baseline | 258 ± 4 | 42.3 ± 2 | 7.36 ± 0.02 |
60 min | 226 ± 26 | 43 ± 2.3 | 7.37 ± 0.01 | |
Time control
+NPC15437 |
baseline | 299 ± 20 | 45.4 ± 1.6 | 7.37 ± 0.02 |
90 min | 290 ± 6 | 45 ± 1.3 | 7.38 ± 0.01 | |
Neural apnea
+ NPC15437 |
baseline | 282 ± 18 | 42.3 ± 1.3 | 7.38 ± 0.01 |
90 min | 303 ± 19 | 42.4 ± 1.4 | 7.40 ± 0.02 | |
Neural apnea
+ BIM |
baseline | 275 ± 6 | 43 ± 0.4 | 7.36 ±0.01 |
90 min | 244 ± 15 | 43.1 ± 0.6 | 7.38 ± 0.03 |