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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Horm Cancer. 2012 Nov 27;4(1):36–49. doi: 10.1007/s12672-012-0127-5

Figure 4. Induction of the KRT5 promoter is specific to progestins, and not other steroids.

Figure 4

T47DK5pLuc cells were treated with various progestins and steroid hormones for 24 h: vehicle (EtOH), 1 µM RU486 (RU), 100 nM P4, 100 nM P4 + 1 µM RU486, 100 nM MPA, 100 nM MPA + 1 µm RU486, 100 nM DHT, 100 nM R1881, 100 nM Dex, or 10 nM E2. Luciferase activity was measured, normalized to total protein per lysate, and plotted as fold induction over vehicle control, ± SEM (n=3). ***p<0.001, one-way ANOVA/Tukey post test.