Table 2.

Experimental and predicted anti-proliferative activity of analogues derived from 2

	SKBr3 (μM)	Predicted (μM)	MCF-7 (μM)
16	1.41±0.20a	0.99	1.58±0.09
17	1.40± 0.07	1.63	1.44± 0.05
18	1.40± 0.11	0.73	1.12± 0.16
19	0.60±0.01	0.58	1.25±0.39
20	3.46±0.02	1.74	5.01±0.01
21a	2.26±0.12	2.00	2.00±0.18
21b	1.67±0.20	1.42	1.62±0.04
21c	1.68±0.12	1.83	2.10±0.08
21d	11.5± 2.0	2.90	11.7±1.0
21e	3.50±0.01	0.97	1.61±0.16
22a	2.43±0.04	1.15	2.17±0.11
22b	0.84±0.18	0.96	1.43±0.08
22e	2.30±0.57	0.33	1.48±0.14

^aValues represent mean ± standard deviation for at least two separate experiments performed in triplicate.