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. Author manuscript; available in PMC: 2013 Feb 7.
Published in final edited form as: J Immunol. 2012 Dec 26;190(3):1048ā€“1055. doi: 10.4049/jimmunol.1202455

Figure 3. Selective depletion of IM results in the loss of the PPS14-specific IgM and IgG, but not PspA-specific IgG, response to intact R614 in chimeric mice.

Figure 3

CD11b-DTR BM chimeric mice (7 mice/group) with or without injection of DT 24 h earlier, were immunized i.p. with R614 (2 Ɨ 108 CFU/mouse in saline). DT was administered every 2ā€“3 d for the duration of the experiment. Mice were boosted with R614 on d 14 in a similar manner. Serum titers of antigen-specific IgM and IgG were measured by ELISA. *Significance pā‰¤0.05. One of three representative experiments.