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Comparison of compound 7 and SL0101 (1) on altering RSK biomarkers in intact cells. Lysates of MCF-7 cells that were pre-treated with inhibitor (SL0101 (100 μM); 7 (25 μM)) and then treated with vehicle (DMSO) or PMA were analyzed by immunoblotting. The arrow indicates a band whose intensity decreases upon treatment of cells with SL0101 (1) and analogue 7.
