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. Author manuscript; available in PMC: 2013 Mar 19.
Published in final edited form as: ACS Med Chem Lett. 2012 Dec 26;4(2):175–179. doi: 10.1021/ml300298v

Table 1.

Pharmacokinetic analysis of SL0101 (1) in male CD-1 mice.

I.V. Dose (mg/kg) AUC/D (ng·h·kg/mL/mg) Co (ng/mL) t1/2 (h)
1 38.7 291 0.15
I.P. Dose (mg/kg) AUC/D (ng·h·kg/mL/mg) Cmax (ng/mL) t1/2 (h)
2.5 1023 1851 0.40

AUC/D: Area Under the Curve, extrapolated to infinity and normalized to the dose in mg/kg; Co (ng/mL): Maximum plasma concentration extrapolated to t=0; Cmax (ng/mL): Maximum plasma concentration; t1/2 (h): half-life.