Table 2.
A. Correlation coefficients between LSD1, cyclinA1 and VEGF-A in prostate cancer specimens. Correlation between LSD1, VEGF-A and cyclinA1 expression in tissue specimens from patients with prostate cancer were determined using the Spearman rank correlation test. Spearman correlation coefficient and p values are shown for each correlation.
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---|---|---|---|---|---|---|
Index | LSD1 | P value | cyclinA1 | P value | VEGF-A | P value |
LSD1 | - | - | −0.067 | ns | 0.315 | 0.019 |
cyclinA1 | −0.067 | ns | - | - | 0.287 | 0.033 |
VEGF-A | 0.315 | 0.019 | 0.287 | 0.033 | - | - |
B. Correlation of LSD1 and JMJD2A with clinical parameters in PCa patients
| ||||||
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LSD1 | JMJD2A | |||||
Low | High | P value | Low | High | P Value | |
Patients (%) | 7 (12 %) | 52 (88 %) | 37 (63 %) | 22 (37 %) | ||
* Age | 63.2 (12 %) | 62.5 (88 %) | 0.78 | 63.1 (62 %) | 61.6 (38 %) | 0.36 |
* PSA | 9.6 (14 %) | 8.5 (86 %) | 0.59 | 9.5 (64 %) | 7.3 (36 %) | 0.11 |
* BCR | 58.4 (12 %) | 30.9 (88 %) | 0.01 | 32.8 (63 %) | 36.3 (37 %) | 0.65 |
* Survival | 65.0 (12 %) | 48.4 (88 %) | 0.21 | 52.8 (63 %) | 46.2 (37 %) | 0.45 |
mean values are presented. Time to biochemical recurrence and survival is indicated in months. Statistically significant associations are indicated in grey. PSA: prostate specific antigen; BCR: biochemical recurrence