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. Author manuscript; available in PMC: 2013 Apr 7.
Published in final edited form as: Molecules. 2012 Jul 10;17(7):8312–8333. doi: 10.3390/molecules17078312

Figure 1.

Figure 1

(a)The binding mode of the core structures with BACE1 enzyme, the former tryptoline core (green) and new tryptamine core (magenta) and (b) the design strategy for multifunctional compounds.