Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Preparation of (S)-3-(-2-amino-3-(1H-1,2,3-triazol-1-yl)propyl)indole (11).
Reagents and conditions: (a) Boc2O, NaOH, THF/H2O (1:1), rt, 18 h; (b) NMM, isobutyl chloroformate, 0 °C, N2, dry THF, 30 min; (c) NaBH4, MeOH, 0 °C, THF; (d) DPPA, DBU, 0 °C, DMF, 30 min; (e) NaN3, 70 °C, DMF, 2 h; (f) TFA, CH2Cl2, 0 °C to rt, 30 min.
