Rhes KO mice are protected from motor dysfunction after 2 days of 3-NP treatment. Time to cross a balance beam (A), number of foot-slips per trial (B), distance travelled before falling (C), and the percentage of trials ending in failure (D) are indicated. *P < 0.05, **P < 0.005, ***P < 0.0005. n = 10 mice per group. No difference in baseline performance or following 1 day of 3-NP treatment was detected between groups.