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. Author manuscript; available in PMC: 2013 Oct 31.

Published in final edited form as: Neuroimage Clin. 2013;2:197–203. doi: 10.1016/j.nicl.2013.01.003

Table 3.

Clinical MRI Observations.

	49,XXXXY (N = 14)		46,XY (N = 42)

	Count	%	Count	%	χ ²	P
Skull Deformity
Craniofacial Disproportion	2	14	0	0	6.2	.013^a ^a
Plagiocephaly	4	29	1	2	8.9	.003^a ^b
Dolichocephaly	1	7	0	0	3.1	.081^a ^a
Thickening of the Calvarium	1	7	0	0	3.1	.081^a ^a
Focal WM Signal Abnormalities
Exclusively Periventricular	1	7	0	0	3.1	.081^a ^a
Periventricular > Subcortical	1	7	0	0	3.1	.081^a ^a
Subcortical > Periventricular	3	21	0	0	9.5	.002^a ^b
Exclusively Subcortical	2	14	1	2	2.9	.087^a ^a
Colpocephaly	9	64	8	19	10.2	.001^a ^b
Prominent Ventricles	4	29	5	12	2.2	.141^a ^a
Periventricular Cyst(s)	3	21	1	2	5.7	.017^a ^a

^a

Statistically significant.

^b

Survived Bonferroni adjustment.