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. Author manuscript; available in PMC: 2013 Apr 29.
Published in final edited form as: J Neurosci. 2012 Apr 4;32(14):4867–4877. doi: 10.1523/JNEUROSCI.5650-11.2012

Figure 7. Absence of RKIP potentiates light-induced expression of PER1 and PER2 in the SCN.

Figure 7

A, C, Representative micrographs of PER1 (A) and PER2 (C) expression in the SCN of RKIP+/+ and RKIP−/− mice 4 h after a 15 min light pulse (LP: 80 lux intensity) at CT 15. Control mice were killed at the same circadian time, CT 19, without receiving a light pulse (DD).B, D, Quantification of PER1 expression in the ventrolateral SCN (B) and PER2 expression in the dorsomedial SCN (C) of light-pulsed (white bars) and dark control (black bars) mice of both genotypes. Values represent mean ± SEM number of immunoreactive nuclei in the designated subregion of the unilateral SCN. n = 4 mice per group. *p < 0.05.