Skip to main content
. Author manuscript; available in PMC: 2013 Sep 27.
Published in final edited form as: J Neurosci. 2013 Mar 27;33(13):5542–5552. doi: 10.1523/JNEUROSCI.5027-12.2013

Figure 4.

Figure 4

Noise-induced threshold shifts, as seen via either DPOAE (A-D) or ABR (E-H). Animals are grouped as defined in Fig. 3. A,E: Animals exposed without prior de-efferentation surgery show small temporary threshold shifts (TTS) when measured immediately (< 1 hr) after exposure (grey circles, A only). However, 1 wk later, thresholds have recovered, as measured by either DPOAEs (A) or ABRs (E). Pre-exposure and 1-wk post-exposure measures are from 10 ears (5 cases); the 1-hr post-exposure measures are from 6 ears (3 cases). B,F: Animals exposed after successful COCB cuts show moderate permanent threshold shifts 1-wk post exposure (n=8 ears from 4 cases), as measured via DPOAEs (B) or ABRs (F). C,G and D,H: Animals exposed after successful LSO injections show moderate permanent threshold shifts 1-wk post exposure, but only in the ear contralateral to the lesion (D,H). Pre-exposure and 1-wk post-exposure measures are means from 17 animals, averaged separately by ear, and segregated into two groups (LOC only vs. LOC & MOC) as described in Fig. 3. For each panel, shifts are computed re mean thresholds for the pre-exposure data from that group. Error bars indicate ± SEM in all panels.