Table 3.

Individual bone volume means and standard deviations.

P0	IPar	R_Par	R_SqT	R_SpA	R_Fro	R_Nas	R_Pal	SqO	R_LaO	BaO	R_PeT	SpB	PrSp	Eth
Un T	0.182 (0.051)	0.403 (0.059)	0.192 (0.026)	0.239 (0.031)	0.762 (0.083)	0.094 (0.029)	0.239 (0.029)*	0.22 (0.05)*	0.417 (0.033)	0.622 (0.044)*	0.08 (0.023)	0.373 (0.035)	0.169 (0.035)	0 (0)
Mu T	0.174 (0.042)	0.383 (0.037)	0.185 (0.013)	0.245 (0.013)	0.788 (0.102)	0.066 (0.029)	0.289 (0.014)*	0.297 (0.027)*	0.422 (0.029)	0.71 (0.026)*	0.065 (0.006)	0.402 (0.02)	0.195 (0.013)	0 (0)
Un MH	0.019 (0.025)	0.076 (0.052)	0.053 (0.03)	0.08 (0.039)	0.256 (0.099)	0.005 (0.006)	0.102 (0.028)	0.022 (0.023)	0.207 (0.067)	0.35 (0.09)	0.013 (0.009)	0.199 (0.063)	0.059 (0.026)	0 (0)
Mu MH	0.023 (0.021)	0.101 (0.052)	0.057 (0.023)	0.106 (0.022)†	0.273 (0.08)	0.002 (0.002)	0.139 (0.017)†	0.058 (0.038)	0.262 (0.021)†	0.444 (0.03)†	0.014 (0.006)	0.237 (0.021)	0.078 (0.011)	0 (0)
Un H	0.001 (0.003)	0.006 (0.008)	0.009 (0.008)	0.012 (0.011)	0.063 (0.046)	0 (0)	0.034 (0.02)	0 (0)	0.04 (0.027)	0.109 (0.05)	0.002 (0.002)	0.044 (0.026)	0.009 (0.008)	0 (0)
Mu H	0.001 (0.002)	0.017 (0.017)	0.01 (0.007)	0.021 (0.014)†	0.072 (0.041)†	0 (0)	0.051 (0.019)†	0.001 (0.001)	0.076 (0.037)†	0.154 (0.05)†	0.003 (0.002)	0.056 (0.028)†	0.012 (0.009)†	0 (0)
P8	IPar	R_Par	R_SqT	R_SpA	R_Fro	R_Nas	R_Pal	SqO	R_LaO	BaO	R_PeT	SpB	PrSp	Eth
Un T	2.135 (0.173)‡	2.226 (0.129)‡	1.375 (0.07)‡	1.075 (0.106)‡	3.407 (0.24)‡	1.112 (0.081)‡	0.842 (0.041)‡	1.939 (0.183)‡	1.241 (0.096)‡	2.005 (0.2)‡	5.934 (0.501)‡	1.673 (0.121)‡	0.736 (0.079)‡	3.611 (0.244)‡
Mu T	0.903 (0.196)‡	0.945 (0.116)‡	0.512 (0.089)‡	0.43 (0.077)‡	1.519 (0.14)‡	0.416 (0.096)‡	0.474 (0.049)‡	0.968 (0.217)‡	0.579 (0.141)‡	1.125 (0.216)‡	2.861 (0.533)‡	0.85 (0.105)‡	0.41 (0.045)‡	2.076 (0.423)‡
Un MH	0.998 (0.368)	0.838 (0.337)	0.608 (0.198)	0.49 (0.138)	1.735 (0.324)	0.416 (0.166)	0.387 (0.083)	0.668 (0.371)	0.662 (0.158)	1.201 (0.174)	2.67 (0.532)	0.993 (0.183)	0.364 (0.081)	1.252 (0.389)
Mu MH	0.256 (0.115)	0.249 (0.103)	0.118 (0.037)	0.075 (0.039)†	0.377 (0.082)	0.044 (0.026)	0.127 (0.028)†	0.126 (0.063)	0.124 (0.053)†	0.428 (0.141)†	0.801 (0.288)	0.249 (0.07)	0.112 (0.036)	0.507 (0.151)
Un H	0.325 (0.289)	0.246 (0.23)	0.161 (0.132)	0.136 (0.098)	0.698 (0.374)	0.069 (0.067)	0.128 (0.075)	0.105 (0.099)	0.216 (0.133)	0.487 (0.269)	0.927 (0.481)	0.393 (0.216)	0.104 (0.08)	0.187 (0.178)
Mu H	0.031 (0.024)	0.039 (0.034)	0.014 (0.009)	0.004 (0.004)†	0.049 (0.021)†	0.002 (0.002)	0.016 (0.007)†	0.003 (0.004)	0.011 (0.008)†	0.072 (0.045)†	0.096 (0.068)	0.028 (0.013)†	0.01 (0.006)†	0.036 (0.041)

Volume mean (standard deviation) for total (T), medium-high density (MH), and high density (H) volumes of individual craniofacial elements of Fgfr2^+/Y394C mutant mice (Mu) and their unaffected littermates (Un) at postnatal day zero (P0) and postnatal day eight (P8). Volumes recorded in mm³. Bone abbreviations are defined in Fig. 4.

^*Denotes significant differences in two-sample t-tests of T bone volume between Un and Mu at P0, where Mu is higher.

^†Denotes values for which there is a net reduction in mean volume between P0 and P8.

^‡Denotes significant differences in two-sample t-tests of T bone volume between Un and Mu at P8, where Un is higher.