Table 1.
Measure | CON | aMCI | AD | Tukey-Kramer1 |
---|---|---|---|---|
Total N | 60 [20/40] | 32 [18/14] | 20 [10/10] | |
Age | 69.7 (7.2) | 70.2 (8.0) | 72.2 (10.2) | ns |
Education | 15.8 (2.6) | 15.3 (3.3) | 13.7 (3.0) | CON vs AD, P < .05 |
CERAD2 | ||||
Animal Fluency | 19.9 (5.0) | 16.2 (5.3) | 11.6 (4.6) | aMCI vs CON, P < .01, aMCI vs AD, P < .001, CON vs AD P < .001 |
Boston Naming Test4 | 27.6 (4.6) | 24.4 (4.1) | 17.9 (8.4) | aMCI vs CON, P < .01, aMCI vs AD, P < .001, CON vs AD P < .001 |
Mini-Mental State Exam4 | 29.2 (1.1) | 27.3 (1.8) | 22.2 (5.0) | aMCI vs CON, P < .001, aMCI vs AD, P < .001, CON vs AD P < .001 |
Word List Memory (WLM)5 | ||||
WLM total | 22.4 (3.5) | 15.3 (4.8) | 14.4 (4.0) | aMCI vs CON, P < .001, CON vs AD P < .001 |
WLM delayed recall | 7.4 (1.7) | 3.1 (2.2) | 2.1 (1.5) | aMCI vs CON, P < .001, CON vs AD P < .001 |
Trail Making Test (TMT) | ||||
TMT-A4 | 33.9 (11.0) | 48.5 (21.4) | 89.3 (57.9) | aMCI vs CON, P < .05, aMCI vs AD, P < .001, CON vs AD P < .001 |
TMT-B4,6 | 86.1 (36.6) | 139.7 (66.9) | 173.4 (98.9) | aMCI vs CON, P < .001, CON vs AD P < .001 |
Digit Span Forward | 8.8 (1.8) | 8.4 (1.6) | 7.7 (2.5) | ns |
Digit Span Backward | 6.9 (2.0) | 5.7 (2.0) | 5.1 (2.1) | aMCI vs CON, P < .05, CON vs AD P < .01 |
Clock Drawing Test | 12.3 (0.9) | 12.2 (0.8) | 7.7 (3.9) | aMCI vs AD, P < .001, CON vs AD P < .001 |
Geriatric Depression Scale7 | 1.6 (1.9) | 2.4 (2.5) | 2.0 (2.3) | ns |
Brackets indicate [male/female]. The mean for each variable is given with standard deviations in parentheses
If the ANOVA F was significant (P < ,05), then the Tukey-Kramer post hoc pair-wise comparisons were performed and P values are given.
CERAD = Consortium to Establish a Registry for Alzheimer’s disease
Animal Fluency: 9 of the AD subjects did not complete/were not administered the test
Variances are not equal and differ significantly
WLM: 32 subjects (aMCI = 8; CON = 15; AD = 9) did not complete/were not administered the test
TMT-B 14 subjects (aMCI = 3; CON = 2; AD = 9) did not complete the test in the allotted timeframe. Scores for these subjects are not included in the TMT-B score
Geriatric Depression Scale: 4 subjects were not administered the GDS