Table 1. Cytokine gene expression in ATI-like cells infected by IAV and MHV-1a.
Fold Change vs. Mockb |
||
---|---|---|
Gene | IAV | MHV-1 |
Bcl6 | 2.8 | 4.0 |
Ccl2 | 2.2 | 3.2 |
Ccl20 | 3.1 | 11.1 |
Ccl4 | 2.1 | 2.0 |
Ccl7 | 2.2 | 3.0 |
Ccl8 | 2.6 | 2.3 |
Ccr3 | 3.2 | 3.8 |
Cxcl1 | 5.0 | 11.5 |
Cxcl10 | 8.0 | 5.2 |
Cxcl13 | 5.6 | 2.1 |
Il10 | 2.4 | 10.7 |
Il16 | 2.8 | 5.8 |
Il1b | 2.1 | 10.3 |
Il1f6 | 3.0 | 3.7 |
Lta | 2.6 | 5.6 |
Ltb | 2.3 | 25.2 |
Tnf | 9.1 | 6.0 |
Tnfrsf1b | 2.7 | 5.2 |
RNA was extracted from IAV or MHV-1 infected ATI-likecells 24 hpi and mRNA for inflammatory cytokines and receptors was quantified by qPCR Array (SABiosciences). Genes included are those with at least a two fold increase compared to mock-inoculated cells in at least two replicate experiments.
Fold change values are representative values from three (IAV) or two (MHV-1) replicate samples.