Table 1.

Differences in protein expression levels in synaptosome fractions between HA-NL1FL and HA-NL1ΔC mice

Protein	% Δ	SEM	p value	Effect Size	Cohen’s d
NL1	183.00	1.23	**0.0004	0.96	7.93
NL3	155.68	56.80	0.2372	0.75	2.29
NR1	118.26	5.00	0.0610	0.76	2.33
NR2A	126.48	3.73	* 0.0161	0.89	3.80
NR2B	109.27	10.36	0.7633	0.48	1.08
GluR1	111.98	4.55	0.0518	0.80	2.71
GluR2	120.86	5.74	0.1127	0.86	3.31
PSD95	103.96	2.83	0.4515	0.57	1.37
PanShank	141.98	12.23	0.1035	0.85	3.29
Gephyrin	108.17	7.12	0.2058	0.51	1.19
PICK1	111.49	4.04	* 0.0370	0.88	3.81
SAP97	125.33	8.71	* 0.0322	0.85	3.17
SAP102	102.26	3.35	0.4964	0.19	0.39
SNAP25	107.86	2.69	0.4745	0.53	1.24
Synapsin1	119.35	2.67	* 0.0185	0.97	7.56
VGLUT1	101.17	1.51	0.0799	0.39	0.85

Summary statistics for levels of all synaptic proteins analyzed from hippocampal synaptosome fractions from controls vs. HA-NL1FL mice. Significance was determined with student’s t-test

^*p < 0.05 and

^**p > 0.01, n = 4 animals in each group.