Table 3.

Design considerations for the establishment of MTT. The specific structure, processes, and functioning of an MTT will differ based on its goals, its membership, and the design features summarized here.

Design Domain	Design Factors for MTTS
Context	Changing institutional support and federal funding Traditional academic structures promote silo based philosophies
Tasks	Scientific inquiry and production requiring high degree of autonomy, interdependence, multidisciplinary thinking, technology mediation, and knowledge management Acceleration of project to individual and population based health impact
Individual Members	Selection based on member personalities: openness, self-efficacy, scientific/academic/social capital Selection based on potential for high scientific and team skills
Skill Acquisition	Core competencies in clinical and translational research
	leadership development
Team Development	Frequently nonlinear and based upon opportunities and needs Based upon collaboration, exchange, active engagement, and is subject to frequent reorientation
Team Structure	Strategic core of team members maintains scientific focus and continuity Loosely coupled networks of internal and external collaborators based on need
Team Processes	Agreed upon charter, vision, goals Agenda based meetings/team documentation Internal and external collaboration/network creation Clarity of roles and responsibilities Acknowledgment and resolution of conflicts and barriers Focus on results and translational goals Empowerment-based leadership and support Effective decision making and problem solving Acknowledgement/use of expertise Focus on development Challenge of process and scientific inquiry
Team Reactions and Affective States	High self-awareness, consensus on team model, knowledge of individual and team-based expertise and capacities Strong commitment to team satisfaction, justice, efficiency, potency, and trust
Team Evolution	Continuous changes promote learning and adaptation Episodic, radical, and unexpected changes creating disequilibrium based change and growth
Team Performance	Accelerated innovation and discovery to address human disease Translation to population based health outcomes