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. Author manuscript; available in PMC: 2014 Mar 13.
Published in final edited form as: J Innate Immun. 2013 Mar 12;5(4):401–413. doi: 10.1159/000347002

Figure 1. GRK5 mediates inflammatory response in cecal ligation and puncture model of polymicrobial sepsis.

Figure 1

GRK5 wild type and knockout mice were subjected to CLP surgery and peritoneal (A) and plasma (B) fluids collected 12 hours after surgery as described in the methods. IL-6, IL-10, TNFα, IL12/23 (total p40), and MCP-1 were measured in these two fluid samples using ELISA kits from eBiosciences. (N=12 for wild type and N=9 for knockouts for the 12 hour timepoint).*P<0.05, **P<0.01 and ***P<0.001 compared to the corresponding septic wild type groups.