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. Author manuscript; available in PMC: 2014 Mar 13.
Published in final edited form as: J Innate Immun. 2013 Mar 12;5(4):401–413. doi: 10.1159/000347002

Figure 5. GRK5 mediates thymocyte apoptosis in polymicrobial sepsis.

Figure 5

Thymi from GRK5 wild type and knockout mice subjected to sham or CLP surgery were collected 20 and 36 hours after surgery as described in the methods. Thymocytes were analyzed for total number (A), CD4+, CD8+ (B), Annexin V+ and PI- staining and for caspase activity (C) as described in the methods. (N=5-6 per genotype for assessing total thymus cell number and Annexin V+ and PI- staining; N=3-4 per genotype for the flow cytometry experiments). *P<0.05, **P<0.01 and ***P<0.001 compared to the corresponding septic wild type groups.