Skip to main content
. Author manuscript; available in PMC: 2013 Aug 15.
Published in final edited form as: J Neurosci. 2013 Jan 2;33(1):358–370. doi: 10.1523/JNEUROSCI.2425-12.2013

Figure 4. Sortilin activity does not affect levels of amyloid-β levels in plasma or levels of amyloid-β peptide degrading enzymes in the brain.

Figure 4

(A) Levels of Aβ40 in plasma of (PDAPP+/−, Sort1+/+) and (PDAPP+/−, Sort1−/−) mice are given. Values are mean ± SEM (n = 4–5 per group). (B) Expression levels of CD10 (neprilysin) and of insulin degrading enzyme (IDE) in hippocampus (Hip) and cortex (Ctx) mice of the indicated genotypes were determined by Western blotting. Detection of tubulin served as loading control.