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. Author manuscript; available in PMC: 2014 Sep 1.

Published in final edited form as: Antiviral Res. 2013 Jun 29;99(3):371–382. doi: 10.1016/j.antiviral.2013.06.014

Table 1.

Antiviral effect of different compounds on influenza viruses in MDCK cells.

Compound	IC₅₀ (nM)^a
Compound	A/PR/8/34 (H1N1)	A/Aichi/2/68 (H3N2)	A/San Diego/1/2009 (H1N1 pdm09)	A/San Diego/21/2008 (H1N1)	A/San Diego/61/2008 (H1N1)	B/Taiwan/2/62
Diphyllin	489.1 ± 14.32	38.32 ± 0.51	632.2 ± 3.67	372.8 ± 8.17	123.6 ± 2.98	139.8 ± 14.68
Amantadine	>22,000	6.14 ± 0.45	NT^b	NT^b	NT^b	NT^b
Oseltamivir	NT^b	NT^b	NT^b	>40,000	NT^b	NT^b

^a

IC₅₀: the concentration of compound showed 50% inhibition of virus-induced cell cytopathic effect (mean ± SD).

^b

NT: not tested.