Table 1.

Significant differences between the major types of lissencephaly for each structure and specific features.

Structure	Groups compared and associated features	p value
Splenium	cLIS – vertical or thin vLIS – absent or thin, and small	p< 0.001
Brain involvement	cLIS – pachygyria (P>A, central, A>P) vLIS – pachygyria entire brain	p< 0.001
Myelination	cLIS - normal vLIS – delayed	p< 0.001
CC genu	cLIS – small inferior or N vLIS – absent or small inferior CBSC – normal genu	p= 0.002
HC	cLIS – normal	p= 0.003
AC	cLIS – normal or small vLIS – absent	p= 0.047
CC body	cLIS – normal or flat thin vLIS – convex upward	p= 0.011