. Author manuscript; available in PMC: 2014 Oct 10.

Published in final edited form as: ACS Med Chem Lett. 2013 Sep 2;4(10):989–993. doi: 10.1021/ml4002858

Table 1.

Pharmacokinetic parameters following either intravenous bolus (IV) or intraperitoneal (IP) injection of BrA (1) in mice (n=3; mean ± SD).

Parameter	Units	IV	IP
Dose	mg/kg	23	23
Kel	h⁻¹	0.93 ± 0.13	-
Kab	h⁻¹	-	0.24 ± 0.03
t_1/2	h	0.75 ± 0.11	-
Cmax	μg/mL		5.8 ± 3.9
Tmax	h	-	1.5
AUC	μg*h/mL	26 ± 5	20
Cp⁰	μg/mL	24 ± 6	-
Vd	L/kg	0.95 ± 0.27	-
Cl	mL/min/kg	16 ± 3	-