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RSLE mutations support L1-mediated neurite outgrowth. L1KO neurons were transfected with wild-type L1 (A), L1ΔARSLE (B), L1-1176 (C), or L1-1180 (D) and plated on an L1 substrate. After 48 hr, neurons were fixed and stained with a monoclonal anti-human L1 antibody (7B5). Scale bar, 100 µm.
