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Expression level of L1 intracellular mutations
| Mutation | L1-1176 | L1ΔRSLE | L1-1180 | L1-1147 | L1-4A | L1-1151Y>A |
|---|---|---|---|---|---|---|
| Percentage expression | 70 ± 12% | 68 ± 9% | 95 ± 12% | 57 ± 7% | 80 ± 12% | 95 ± 9% |
Mutant expression level is expressed as a percentage compared with L1KO neurons transfected with WT hL1. Neurite total expression is from neurites fixed and permeabilized and then stained with a monoclonal antibody that recognizes human L1 (7B5). All values are given as mean ± SEM.
