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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Biochim Biophys Acta. 2013 Sep 18;1838(4):1058–1067. doi: 10.1016/j.bbamem.2013.09.004

Table 1.

List of identified viroporin proteins a

Name of
virus		 Name of viroporin # of
amino
acid		 Oligomeric
state		 Ion or
Substrate		 References
IAV M2 97 tetramer H+ Ref [37, 38, 74]
IBV BM2 115 tetramer H+ Ref [39]
HCV p7 63 hexamer cation Ref [18, 62]
HIV-1 Vpu 81 pentamer cation Ref [70, 71, 90]
SARS-CoV 3a 274 tetramer K+ Ref [72]
E 76 pentamer Na+, K+ Ref [91]
alphavirus 6K 61 N/Ab Na+, K+, Ca2+ Ref [8]
poliovirus VP4 68 N/Ab RNA Ref [23]
2B 97 N/Ab Ca2+ Ref [7, 92]
HPV E5 83 N/Ab N/A Ref [93, 94]
PBCV-1 Kcv 94 tetramer K+ Ref [21, 95]
a

The viruses listed are influenza A virus (IAV), influenza B virus (IBV), hepatitis C virus (HCV), human immunodeficiency virus type 1 (HIV-1), severe acute respiratory syndromes-associated coronavirus (SARS-CoV), alphavirus, poliovirus, human papillomavirus (HPV), and paramecium bursaria chlorella virus 1 (PBCV-1).

b

Pore formation indicated but a defined oligomeric state either does not exist or is not characterized.