Table 1.

Known effects of defensins on virus infection.

Virusa	Envb	HNPc				HDc		HBDc				References
		1	2	3	4	5	6	1	2	3	4
CMV	Y	I	*	*	*	*	*	*	*	*	*	[1]
HIV-1	Y	I	I	I	I	E	E	NE	I	I	*	[52, 66, 83]
HPIV-3	Y	*	*	*	*	*	*	NE	I	*	*	[73]
HSV-1/-2	Y	I	I	I	I	I	I	NE	NE	I	*	[1, 44]
IAV	Y	I	I	I	I	I	I	I	I	*	*	[48, 97, 98]
RSV	Y	*	*	*	*	*	*	NE	I	*	*	[73]
VSV	Y	I	*	*	*	*	*	*	*	*	*	[1]
VV	Y	NE	*	*	*	*	*	NE	NE	I	*	[73, 93, 129]
VZV	Y	*	*	*	*	*	*	*	I	*	*	[92]
AAV	N	I	I	*	*	*	*	*	*	*	*	[36]
Echovirus	N	NE	*	*	*	*	*	*	*	*	*	[1]
HAdV-	N
A		I	*	*	*	I	*	*	*	*	*	[45, 58, 165, 166]
B		I	*	*	*	I	*	NE	NE	*	*
C		I	*	*	*	I	*	NE	NE	*	*
D		E	*	*	*	E	*	NE	NE	*	*
E		E	*	*	*	I	*	*	*	*	*
F		E	*	*	*	NE	*	*	*	*	*
HPV	N	I	I	I	I	I	NE	NE	NE	*	*	[59]
PyV-	N
BKV		I	*	*	*	I	*	NE	I	*	*	[60]
JCV		I	*	*	*	I	*	I	I	*	*
SV40		NE	*	*	*	I	*	NE	NE	*	*
HRV	N	*	*	*	*	*	*	*	NE	*	*	[39]
Reovirus	N	NE	*	*	*	*	*	*	*	*	*	[1]

^aCMV, cytomegalovirus; HIV, human immunodeficiency virus; HPIV, human parainfluenza virus; HSV, herpes simplex virus; IAV, influenza A virus; RSV, respiratory syncytial virus; VSV, vesicular stomatitis virus; VV, vaccinia virus; VZV, varicella zoster virus; AAV, adeno-associated virus; HAdV, human adenovirus; HPV, human papillomavirus; PyV, polyomavirus; BKV, BK virus; JCV, JC virus; SV40, simian virus 40; HRV, human rhinovirus

^benveloped (Y) or non-enveloped (N) virus

^cHNP, human neutrophil peptide; HD, human defensin; HBD, human β-defensin; I, inhibit; E, enhanced;*, not tested; NE, no effect