TABLE I.

The fitted model parameters of susceptibility evolutions in white matter

		χ = A ×age ×exp(−age=B) +C
		A (ppb/year)	B (year)	C (ppm)
IC	Male	−2.2 ± 1.1	41 ± 8	−0.03 ± 0.01
	Female	−1.6 ± 0.9	46 ± 11	−0.03 ± 0.01
	Both	−1.7 ± 0.7	45 ± 8	−0.03 ± 0.01
	Both (>7 y/o)	−1.0 ± 1.6	46 ± 26	−0.04 ± 0.02
SCC	Male	−1.9 ± 1.0	29 ± 6	0.00 ± 0.01
	Female	−1.5 ± 1.0	35 ± 8	0.00 ± 0.01
	Both	−1.6 ± 0.7	32 ± 5	0.00 ± 0.01
	Both (>7 y/o)	−2.6 ± 1.8	33 ± 7	0.01 ± 0.02
OR	Male	−2.7 ± 0.9	26 ± 4	−0.02 ± 0.01
	Female	−1.4 ± 1.0	24 ± 11	−0.03 ± 0.01
	Both	−2.0 ± 0.7	26 ± 4	−0.03 ± 0.01
	Both (>7 y/o)	−2.3 ± 1.7	27 ± 9	−0.02 ± 0.02
SC-WM	Male	−3.0 ± 1.1	23 ± 4	−0.01 ± 0.01
	Female	−2.3 ± 1.1	25 ± 6	−0.01 ± 0.01
	Both	−2.4 ± 0.8	25 ± 4	−0.01 ± 0.01
	Both (>7 y/o)	−2.6 ± 0.9	27 ± 4	−0.01 ± 0.01
MC-WM	Male	−1.1 ± 0.8	40 ± 12	−0.01 ± 0.01
	Female	20.8 ± 0.7	43 ± 16	−0.02 ± 0.01
	Both	−0.9 ± 0.5	43 ± 10	−0.02 ± 0.00
	Both (>7 y/o)	−1.3 ± 0.7	42 ± 7	−0.01 ± 0.01

Note: Values were reported as the fitted parameter ± 95% confidence bounds. Male (Female): when only male (female) subjects were included in the analysis. Both: when all subjects were included. Both (>7 y/o): when only subjects older than 7 y/o were included.