. Author manuscript; available in PMC: 2014 Mar 7.

Published in final edited form as: Cell Mol Life Sci. 2013 Sep 18;71(5):831–845. doi: 10.1007/s00018-013-1470-6

Table 1.

Carbonic anhydrases as carbon dioxide sensors

Species	Carbonic anhydrase isoform	Evidence	Downstream effector	References
Fungi: Cryptococcus neoformans	Can2	Genetic	Bicarbonate	[44]
Fish		Pharmacological: acetazolamide	Protons	[69]
Plants	CA1, CA4, unrelated mammalian CA	Genetic	Bicarbonate	[34]
Bacteria: Vibrio cholerae		Pharmacological: ethoxzolamide	Bicarbonate	[31]
Mammals: mouse smell	CAII	Genetic	Bicarbonate	[84]
Mammals: mouse taste	Car4	Genetic	Protons	[85]