The adjuvant effect of intranasally administered ambient UFP on OVA sensitization was further enhanced in Nrf2-/- mice. A. Increased BAL cell count including total cell number, eosinophils and lymphocytes, *p < 0.02 compared with respective saline control, ap < 0.05 compared with respective OVA. B. Elevated OVA-IgG1 level in the blood, *p < 0.01 compared with respective saline control, ap < 0.01 compared with respective OVA. C. Increased OVA-IgE production, *p < 0.01 compared with respective saline control, ap < 0.05 compared with respective OVA. D. Increased IL-13 level in the BAL fluid, *p < 0.05 compared with all other groups.