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. Author manuscript; available in PMC: 2014 Jan 15.
Published in final edited form as: WormBook. 2013 Jun 4:1–34. doi: 10.1895/wormbook.1.45.2

Figure 1. A hypothetical RNAPII elongation megacomplex.

Figure 1

RNAPII (including the extended CTD with SerPO4 knobs) is purple; the globular and CTD portions are drawn approximately to scale for mammalian RNAPII. Orange DNA is wrapped around yellow nucleosomal histones; nucleosomes modified by Set2 are shaded darker. The nascent RNA transcript is green. Yeast names are used for PCAPs (e.g., Phatnani and Greenleaf, 2006; PMID 17079683), not all of which are shown. (CBC) cap-binding complex; (CRF) chromatin remodeling factor; (XF) processing/export factor. (Used with permission Phatnani and Greenleaf, 2006; PMID 17079683)