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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Mol Oncol. 2013 Oct 28;8(1):142–149. doi: 10.1016/j.molonc.2013.10.007

Figure 6.

Figure 6

Effect of exposure to various concentrations of 5-FU and docetaxel on various cell lines in relation to their ability to form tumor spheres (CSC property). Cells that readily formed tumor spheres (OAPC and JHESO) were more resistant to cytotoxics than those cells that had difficulty forming tumor spheres (FLO-1). A. Response of various cell lines to various concentrations of 5-FU. B. Response of various cell lines to various concentrations of docetaxel. C. Tumor sphere assay were done in triplicate in ultra-low attachment plates and tumor spheres were counted after 8-10 days in culture. D. Bar graph showing tumor sphere formation ability of various cell lines.