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Upregulation of ALDH-1 when SKGT-4 and YES-6 cells are made resistant to 5-FU. A. Overexpression of ALDH1 and other CSC-related genes (YAP1 and Gal-3) if cells were resistant to 5-FU at different concentrations. B. 5-FU response of SKGT-4 parenteral cells and made resistant cells using MTS cell proliferation assay. C. 5-FU response of YES-6 parenteral cells and made resistant cells using MTS cell proliferation assay.
