Table 1.
Characteristics of 249 Patients with Suspected DILI Undergoing Biopsy
| N (%) | ||
|---|---|---|
| Female | 144 (57.8) | |
| Age (mean, range) | 48 (7 – 87) | |
| Agents Implicated | ||
| Single Agent | 172 (69.1) | |
| Two Agents | 56 (22.5) | |
| ≥ Three Agents | 21 (8.4) | |
| Most Common Agents Implicated | ||
| Amoxicillin/Clavulanate | 19 (7.6) | |
| Nitrofurantoin | 11 (4.4) | |
| Sulfamethoxazole/Trimethoprim | 9 (3.6) | |
| Minocycline | 8 (3.2) | |
| Ciprofloxacin | 7 (2.8) | |
| Anabolic Agents | 6 (2.4) | |
| Azithromycin | 5 (2) | |
| Levofloxacin | 5 (2) | |
| Causality Process Completed | 208 (83.5) | |
| Definite | 53 (21.3) | |
| Very Likely | 84 (33.7) | |
| Probable | 33 (13.3) | |
| Possible | 24 (9.6) | |
| Unlikely | 14 (5.6) | |
| DILIN Severity Score | ||
| Mild | 40 (16.1) | |
| Moderate | 39 (15.7) | |
| Moderate-Hospitalized | 83 (33.3) | |
| Severe | 31 (12.5) | |
| Fatal/Transplanted | 15 (6.0) | |