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. Author manuscript; available in PMC: 2014 Jan 17.
Published in final edited form as: Mo Med. 2013 Jul-Aug;110(4):325–330.

Figure 2.

Figure 2

Label-free technology for monitoring cellular events. (A) MIF (red) binds to receptors on the cell surface and activates the intracellular signaling events represented as dynamic mass redistribution (DMR, black indicates movement of signaling molecules). Cells are plated on a fibronectin-coated biosensor. (B) DMR is represented as the peak wavelength value difference (delta PWV) before and after the addition of MIF. (C) One of the HTS MIF inhibitors alters the MIF-mediated DMR responses compared to those of MIF alone in panel B.