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. Author manuscript; available in PMC: 2015 Jan 20.
Published in final edited form as: Virology. 2013 Dec 12;449:235–243. doi: 10.1016/j.virol.2013.11.025

Figure 3. MHC expression by NPCs in response to JHMV infection.

Figure 3

Cultured GFP NPCs were infected with JHMV (m.o.i.=0.1) for 18 hours and subsequently replenished with media alone or containing 100 U/ml IFN-γ. Cells were incubated for 24 h and MHC class I/II expression of non-infected and infected NPCs evaluated via flow cytometry. The frequency of NPCs expressing either MHC class I (A) or MHC class II (B) is shown in representative dot plots. (C) Quantification of the frequency of MHC I/II expression by infected or non-infected NPCs treated with media alone or in combination with IFN-γ. Data is presented as average ± SEM and represents 3 independent experiments (*p < 0.05).(D) Representative dot plots of MHC II-positive NPCs versus JHMV-positive NPCs.