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. Author manuscript; available in PMC: 2015 Jan 20.
Published in final edited form as: Virology. 2013 Dec 12;449:235–243. doi: 10.1016/j.virol.2013.11.025

Figure 4. Virus-specific CD8+ T cells target S510–518 pulsed NPCs for lysis.

Figure 4

CTLs were harvested from mice immunized with the DM variant of JHMV and co-cultured at varying effector:target ratios with S510–518 pulsed, IFN-γ-treated NPCs for 4 hours, and lactate dehydrogenase released into the supernatant was subsequently measured. Non-IFN-γ-treated RMA/S cells pulsed with 50µM S510–518 were used as a positive lysis control.