Table 2. Plasma oxidized amino acid concentrations.
| Fabry disease (n = 13) | Controls (n = 11) | |
|---|---|---|
| 3-nitrotyrosine | 38.1 (13.6-78.9)* | 6.0 (1.7-14) |
| chlorotyrosine | 1.6 (0.03-74.5) | 1.5 (0.4-50.3) |
| Dityrosine | 15.2 (12.6-19.5) | 15 (12.9-21) |
| meta-tyrosine | 0.2 (0.1-31.8) | 15.8 (0.01-72.9) |
| ortho-tyrosine | 16.2 (11-33.1) | 18.1 (7.4-86.1) |
The oxidized amino acid concentrations were assayed as described in the MATERIALS AND METHODS section. The data are expressed as μmol/mmole of total protein tyrosine and represent medians (range) of triplicate assays performed twice per sample.
p < 0.01.