Table 2.

Inhibition by ApAP of Hemeprotein-Catalyzed Oxidation of Arachidonic Acid^a

analogue	ApAP	12	13	14
Mb (µM ± SEM)	2.3 ± 0.2b	1.2 ± 0.1	2.3 ± 0.4	5.3 ± 0.1
COX-1 (µM ± SEM)	372c	451 ± 35	>1000	198 ± 25

^aThe inhibition of the lipid peroxidation produced by myoglobin (Mb) and COX-1 by the different analogues was tested as described previously.^2,3 Values represent the IC₅₀ for each hemeprotein and are expressed as means ± SEM.

^bValue reported in ref 3.

^cValue reported in ref 2.