Figure 2. Top six acute myeloid leukemia associated antigens.
A) Therapeutic or diagnostic threshold for leading antigen candidates. Expression of antigens in all acute myeloid leukemia samples (AML) compared to all normal donor samples (ND) as box-plots where box represents 25th to 75th percentile and whiskers represent maximum and minimum dCT values observed. B) Detailed characteristics of leading AML antigen candidates including what percentage of AML samples tested had at least 5x overexpression (OE) of that gene, average levels of OE and OE in sorted lineage negative, CD34 positive and CD38 negative cells and normal donor tissues (see supplement for additional details).