Table 3. Changes in Volumetric Functional Metrics and Anatomic Metrics.

Parameter	Before Treatment	After Treatment	Median Percentage Change	P Value*
Anatomic metric
RECIST	7.9 cm ± 4.4	7.4 cm ± 4.4	−8.6	<.002
mRECIST	6.5 cm ± 3.7	5.2 cm ± 3.7	−18.2	<.0001
EASL	42.2% ± 47.1	25.8% ± 39.1	−47.9	<.0001
Volumetric functional metric
Volumetric ADC	1.24 × 10−3 mm/sec2 ± 0.313	1.55 × 10−3 mm/sec2 ± 0.417	20.3	<.0001
Volumetric arterial enhancement	54.2% ± 42.3	31.5% ± 32.6	−33.2	<.0001
Volumetric venous enhancement	82.5% ± 31.2	60.4% ± 33.7	−16.7	<.0001

Note.—Unless otherwise indicated, data are means ± standard deviations. There were significant changes in tumor size according to RECIST and enhancement according to EASL and mRECIST, but their median percentage change did not fulfill the partial response according to respective criteria.

^*P value indicates changes in pretreatment and 3–4-week posttreatment data analyzed by using a paired Student t test.