Table 3.
Multivariable Logistic Regression Results Predicting Early Non-Adherence to Antihypertensives
| Class | % Early Non- Persistence to Antihypertensives | Odds Ratios (95% CI) |
|---|---|---|
| Race: | ||
| White | 30.6 | Referent |
| Black | 42.5 | 1.58 (1.45 – 1.72)** |
| Asian | 38.1 | 1.38 (1.27 – 1.49)* |
| Hispanic | 41.1 | 1.47 (1.37 – 1.59)** |
| Other/Mixed/Unknown | 11.3 | 1.06 (1.01 – 1.12)** |
| Age: | ||
| <50 | 39.1 | |
| 50–64 | 28.7 | 0.67 (0.64 – 0.70)** |
| 65–74 | 28.1 | 0.66 (0.61 – 0.71)** |
| 75+ | 31.1 | 0.76 (0.68 – 0.85) |
| Gender: | ||
| Male | 33.1 | |
| Female | 32.8 | 0.92 (0.88 – 0.96)** |
| Current Smoker: | ||
| No | 32.3 | Referent |
| Yes | 38.8 | 1.16 (1.09 – 1.24)** |
| BMI: | ||
| <24.99 | 37.3 | Referent |
| Overweight (25– 29.99) | 35.7 | 0.90 (0.84 – 0.97)** |
| Obese (≥30) | 36.2 | 0.84 (0.79 – 0.90) |
| Missing | 24.8 | 0.63 (0.58 – 0.69)** |
| Baseline SBP | ||
| <140 | 33.5 | |
| 140 – 149 | 36.4 | 1.07 (1.02 – 1.13)** |
| 150 – 159 | 33.3 | 0.96 (0.90 – 1.02)* |
| 160+ | 32.2 | 0.99 (0.93 – 1.06) |
| Household Income: | ||
| < $40K | 35.9 | Referent |
| $40K – $ 74.9K | 33 | 0.90 (0.85 – 0.95) |
| ≥ $75K | 30.9 | 0.86 (0.80 – 0.91)* |
| Missing | 32.1 | 1.10 (0.79 – 1.52) |
| Drug Copay | ||
| <$6 | 32.9 | Referent |
| $6–10 | 33.9 | 1.06 (1.01 – 1.11)** |
| $11+ | 29.1 | 0.96 (0.88 – 1.04) |
| Comorbid Conditions: | ||
| Diabetes | 37.9 | 1.09 (1.00 – 1.18)* |
| CKD | 33.6 | 1.02 (0.88 – 1.19) |
| Prior CVD | 31.8 | 0.91 (0.79 – 1.06) |
| Concurrent Depression | 38.4 | 1.08 (0.96 – 1.21) |
| Ever Schizophrenia | 32.4 | 0.77 (0.53 – 1.11) |
| Ever Bipolar Disorder | 38.1 | 1.03 (0.81 – 1.32) |
| Ever Anxiety | 38.9 | 1.09 (1.00 – 1.19) |
| Total outpatient visits: | ||
| 0 | 27.7 | Referent |
| 1 to 2 | 34.6 | 1.03 (0.97 – 1.10)** |
| 3 to 5 | 36.3 | 1.09 (1.02 – 1.18) |
| 6 to 15 | 40.9 | 1.30 (1.19 – 1.43)** |
*
p-value ≤ 0.05
**
p-value ≤ 0.01