Table 4.
Multivariable Logistic Regression Results Predicting Early Non-persistence to Antihypertensives Among Patients with History of Depression
| Class | Proportion non-persist | |
|---|---|---|
| Race: | ||
| White | 36.3 | |
| Black | 50.5 | 1.65 (1.02 – 2.66) |
| Asian | 46.5 | 1.42 (0.89 – 2.27) |
| Hispanic | 39.4 | 0.97 (0.66 – 1.41) |
| Other/Missing | 36.5 | 1.07 (0.81 – 1.42) |
| Age: | ||
| <50 | 43.8 | |
| 50–64 | 33.1 | 0.65 (0.51 – 0.84) |
| 65–74 | 34.4 | 0.62 (0.39 – 0.98) |
| 75+ | 41.9 | 0.82 (0.45 – 1.49) |
| Gender: | ||
| Male | 37.4 | |
| Female | 39 | 1.04 (0.81 – 1.32) |
| Smoker: | ||
| No | 38.2 | |
| Yes | 39.1 | 1.02 (0.75 – 1.39) |
| BMI: | ||
| <24.99 | 42.5 | |
| Overweight (25– 29.99) | 39.4 | 0.91 (0.64 – 1.29) |
| Obese (≥30) | 38.5 | 0.85 (0.61 – 1.19) |
| Missing | 26.4 | 0.72 (0.38 – 1.38) |
| Baseline SBP: | ||
| <140 | 38.6 | |
| 140 – 149 | 39.6 | 1.05 (0.79 – 1.40) |
| 150 – 159 | 36.2 | 0.94 (0.68 – 1.31) |
| 160+ | 42.8 | 1.22 (0.84 – 1.77) |
| Household Income: | ||
| < $40K | 39.9 | |
| $40 – $ 74.9K | 37.8 | 0.97 (0.72 – 1.31) |
| ≥ $75K | 38.5 | 1.01 (0.71 – 1.43) |
| Copay: <$6 | 36.9 | |
| $6–10 | 38.9 | 1.10 (0.85 – 1.42) |
| $11+ | 38.5 | 1.15 (0.74 – 1.77) |
| Comorbidity: | ||
| Diabetes | 39.1 | 1.01 (0.65 – 1.57) |
| CKD | 39.4 | 0.88 (0.37 – 2.08) |
| Prior CVD | 46.3 | 1.84 (0.92 – 3.67) |
| Ever Schizophrenia | 25 | 0.25 (0.03 – 2.20) |
| Ever Bipolar Disorder | 29.6 | 0.64 (0.26 – 1.61) |
| Ever Anxiety | 42.3 | 1.11 (0.80 – 1.52) |
| Total visists: | ||
| 0 | 25.5 | |
| 1 to 2 | 35.4 | 1.08 (0.57 – 2.05) |
| 3 to 5 | 40.3 | 1.20 (0.63 – 2.31) |
| 6 to 15 | 42.5 | 1.27 (0.65 – 2.50) |
| No Antidepressant use | 43 | |
| Antidepressant use; not persistent for 6 months | 42.8 | 0.92 (0.61 – 1.37) |
| Antidepressant use; persistent for 6 months | 32.1 | 0.64 (0.42 – 0.96)** |
*
p-value ≤ 0.05
**
p-value ≤ 0.01