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. Author manuscript; available in PMC: 2008 Nov 28.
Published in final edited form as: J Neurosci. 2008 May 28;28(22):5762–5771. doi: 10.1523/JNEUROSCI.0575-08.2008

Figure 2.

Figure 2

Gabapentin (50 μM) and ethanol additively augment IPSC amplitudes in CeA from non-dependent rats. A: Pooled data from 5 CeA neurons show that ethanol (44 mM) co-applied with gabapentin further increased GABA-IPSC amplitudes, suggesting that gabapentin and ethanol may use different intracellular mechanisms to augment GABA-IPSCs. B: Gabapentin (50 μM) significantly (p < 0.05; n = 7) decreased the mean paired-pulse ratio, and ethanol further significantly (p < 0.05; n = 7) decreased it, with recovery on washout. Ethanol alone also significantly (*p < 0.05) decreased PPF of GABA-IPSCs (n = 6) as we have previously shown {Roberto, 2003 #379}.