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. Author manuscript; available in PMC: 2008 Nov 28.
Published in final edited form as: J Neurosci. 2008 May 28;28(22):5762–5771. doi: 10.1523/JNEUROSCI.0575-08.2008

Table 1.

Time spent ± SEM in the open and closed arms of the elevated plus-maze and closed arm entries ± SEM by rats injected i.p. with one of two doses (0.0, 3.0 g/kg) of 10% w/v ethanol. The plus-maze test was administered 10 hours following ethanol injection, and 30 minutes following i.p. injection with one of four gabapentin doses (0, 30, 60, 120 mg/kg). The plus-maze test lasted 300 seconds in total duration.

Ethanol Dose Gabapentin Dose n Time spent in open arms (sec) Time spent in closed arms (sec) Closed arm entries
0.0 g/kg
0 mg/kg 8 35.70 ± 12.02 101.30 ± 18.26 26.00 ± 3.78
30 mg/kg 7 42.60 ± 9.51 112.90 ± 7.61 23.71 ± 1.95
60 mg/kg 8 54.75 ± 12.77 126.38 ± 5.53 23.13 ± 3.07
120 mg/kg 8 29.00 ± 12.47 148.75 ± 6.44 19.88 ± 8.46
3.0 g/kg *
0 mg/kg 8 14.10 ± 6.39 189.00 ± 20.39 19.75 ± 3.85
30 mg/kg 7 24.30 ± 10.97 148.80 ± 34.33 20.14 ± 2.68
60 mg/kg 8 31.38 ± 11.45 164.63 ± 25.46 9.63 ± 2.35
120 mg/kg 8 43.00 ± 16.54 130.00 ± 27.53 13.25 ± 4.86
*

p<0.05 significant main effect of ethanol on closed arm entries.