Skip to main content
. Author manuscript; available in PMC: 2009 May 11.
Published in final edited form as: J Neurosci. 2008 May 28;28(22):5827–5835. doi: 10.1523/JNEUROSCI.1236-08.2008

Figure 1. Zinc triggers microglia activation.

Figure 1

(A) Resting microglia have multiple branched processes, whereas microglia incubated for 90 minutes with 30 μM zinc or 50 ng / ml LPS show retracted processes and a rounded, “amoeboid” morphology. Scale bar = 10 μm. (B) ZnCl2 has a concentration-dependent effect on the fraction of microglia exhibiting the activated morphology. (C) ZnCl2 effects on microglial survival, assessed 24 hours after a 90-minute exposure. n = 4; p < 0.01 versus control.